CN
/
EN
Contact Us
Blog
Application and innovation of fermentation system technology in the biopharmaceutical industry
2024-11-14

Fermentation system technology, as an important bioengineering technology, has a wide range of applications in the field of biopharmaceuticals. This paper mainly discusses the application status quo, development trend, key technological innovations and challenges faced by fermentation system technology in the biopharmaceutical industry.


The biopharmaceutical industry is an important part of China's strategic emerging industries, which has high scientific and technological content and industrial added value. Fermentation system technology, as one of the core technologies of the biopharmaceutical industry, is of great significance in promoting the development of the biopharmaceutical industry. With the continuous progress of biotechnology, the application of fermentation system technology in the biopharmaceutical industry is becoming more and more widespread, providing strong support for the innovation and development of China's biopharmaceutical industry.

Application of fermentation system technology in the biopharmaceutical industry

Microbial drug fermentation production

Fermentation system technology plays an important role in microbial drug production. Through fermentation systems, microbial drugs such as antibiotics, vaccines, enzymes, etc. can be efficiently produced to meet clinical needs.

Cell culture and metabolic regulation

Fermentation system technology has a wide range of applications in cell culture and metabolic regulation. The use of fermentation system for cell culture can realize the large-scale production of bioactive substances, such as insulin and growth factors.

Genetically engineered drug fermentation production

Fermentation system technology has an important position in genetically engineered drug production. Through the fermentation system, recombinant proteins, monoclonal antibodies and other genetically engineered drugs can be produced to provide new means for disease treatment.

Biotransformation and biosynthesis

Fermentation system technology has a great potential in biotransformation and biosynthesis. Using the metabolic pathways of microorganisms, biotransformation and synthesis of drug precursors, chiral compounds, etc. can be achieved.

Fermentation system technology innovation and development trend

Fermentation process optimization and control

Fermentation process optimization and control is the key to improve fermentation efficiency. In recent years, researchers have deeply analyzed the microbial metabolic network through genomics, metabolomics and other technologies to provide a theoretical basis for fermentation process optimization.

Fermentation equipment research and development

Fermentation equipment is an important part of fermentation system technology. The research and development of efficient, energy-saving and environmentally friendly fermentation equipment helps to reduce production costs and improve drug quality.

Microbial resource mining and utilization

Microbial resource mining and utilization is an important direction of technological innovation of fermentation system. By screening microorganisms with special functions, the application of fermentation system technology in the field of biopharmaceuticals can be broadened.

Fermentation process innovation

Fermentation process innovation is the key to promote the development of fermentation system technology. Researchers have continuously explored novel fermentation processes, such as solid-state fermentation, liquid fermentation, and gas fermentation, to improve fermentation efficiency.

Challenges and Suggestions for the Development of Fermentation System Technology in China

Challenges

(1) The basic research on fermentation system technology is relatively weak, and the innovation ability is insufficient.

(2) The level of R&D of fermentation equipment needs to be improved, and high-end fermentation equipment is dependent on imports.

(3) The fermentation process control and optimization technology is in need of a breakthrough.

Suggestions

(1) Increase the investment in basic research on fermentation system technology and improve the innovation ability.

(2) Promote the cooperation between industry, academia and research, and promote the transformation of fermentation system technology results.

(3) Cultivate fermentation system technical talents and improve the quality of talents.

(4) Strengthening international cooperation and exchanges, and introducing foreign advanced technology.



There is a broad prospect for the application of fermentation system technology in the biopharmaceutical industry. China should seize the opportunity to increase research and development efforts to promote fermentation system technology innovation and provide strong support for the high-quality development of China's biopharmaceutical industry. At the same time, we should actively respond to the challenges facing the development of fermentation system technology and contribute to the innovation and development of China's biopharmaceutical industry.

Other info