Fermentation system is a key technology in the field of bioengineering, which transforms raw materials into valuable products through the metabolic activities of microorganisms. With the continuous innovation of biotechnology, fermentation systems have achieved remarkable results in improving product quality, reducing production costs, and realizing green production. In this paper, we will discuss the new trends of fermentation systems in innovation and development, the challenges they face, and how to promote the bio-industry towards high-quality development.

Trends in the innovation of fermentation systems

strain engineering

{{21 21}}

With the rapid development of gene editing technology, strain engineering has become an important direction of fermentation system innovation. Through genetic modification, the fermentation performance and product specificity of strains are improved to realize efficient and specialized production process.

Fermentation process optimization

The use of metabolic engineering, systems biology, and other means to optimize the fermentation process, improve the yield and conversion of the target product, and reduce the generation of by-products.

Modernization of fermentation equipment

Fermentation equipment to large-scale, automated, intelligent direction to improve the production efficiency and stability, and reduce manual intervention.

Challenges to the fermentation system

Strain stability and safety

Strains may mutate during the process of passing on the strain, which may affect the fermentation performance. Meanwhile, the safety of transgenic strains is also of great concern.

Complexity of fermentation process control

The fermentation process involves a variety of factors, such as temperature, pH, dissolved oxygen, nutrients, etc., which makes it a major challenge to achieve precise control and improve the fermentation efficiency.

Production cost and market competitiveness

Reducing production cost and improving product market competitiveness are important issues facing fermentation systems. This requires comprehensive consideration from raw materials, energy, equipment and other aspects.

Strategies for fermentation systems to promote the high-quality development of the bio-industry

Strengthening strain research and development and improvement

Continuously carry out the screening of bacterial strains and the modification of genetic engineering to cultivate more high-performance and safe fermentation strains.

Optimize the fermentation process and control strategy

Combine with big data, artificial intelligence and other technologies to realize real-time monitoring and intelligent control of the fermentation process, and improve production efficiency.

Promote green fermentation technology

Develop low-carbon, environmentally friendly fermentation technology, reduce waste emissions, and achieve sustainable development of the fermentation industry.

Expand the application fields of fermentation products

Increase the R&D of fermentation products in the fields of pharmaceuticals, food, agriculture, and environmental protection, and broaden the market space.

Fermentation system, as the core technology of the bio-industry, its innovation and challenges are of great significance to the development of the whole industry. In the face of the requirements of the new era, China's fermentation industry should seize the opportunity to increase R&D investment, promote the continuous innovation of fermentation technology, and provide a strong impetus for the high-quality development of the bio-industry. Through the combination of industry, academia, research and utilization, we can cultivate a number of fermentation enterprises with international competitiveness, and help China's bio-industry to go to the world stage.