In the pharmaceutical field, the emergence of single-use systems dates back as far as the 1940s. And single-use bioreactors (SUBs)/fermentation equipment, which are at the heart of biotechnology production, have gradually become the focal point of single-use systems. Since the late 1990s, commercial single-use bioreactors have been in use and are trending towards being more widespread and ubiquitous.

JC-SUBseries (disposable) bioreactors

JiChen BioResearch developed and produced JC-SUBseries bioreactors are based on the concept of "single-use system". 20}} series bioreactors are designed based on the traditional bioreactor mixing principle, combining the mixing and cultivation effect of traditional mixing and the superior performance of disposable process equipment free from cleaning and sterilization verification. Hardware, software and consumables form an efficient, easy-to-use and powerful cell culture platform to achieve optimal cell growth, cell viability and metabolism, with specifications ranging from 50L-2000L to meet the needs of R&D, pilot testing, clinical reporting and commercial production.

Product features and advantages

1.Series can be scaled up to 50L-2000L, customized options to meet the needs of different processes

2.It is suitable for suspension cell and microsphere adherent cell culture processes such as CHO, 293, SF-9, etc.

3. disposable bioreaction bags and other consumables to support customization

4. the use of Siemens PLC, high-performance hardware configurations, modular design, to enhance the security and integrity of the data, the system is stable

5. the three levels of authority, audit Tracking, support with third-party system signal interaction

6. support for process development and amplification, to provide upstream process solutions

7. touch-screen software control features rich, simple and intuitive, feedback system logic clear

8.Top and bottom ventilation with disposable reaction bag chassis design, flexible adjustment of ventilation strategy

9.Provide complete FAT, SAT, IQ/OQ documents and service

Application Scenarios

JC-SUB SeriesBioreactors have been developed and tested for mammalian cell and microbial cultures for use in the fields of antibodies, vaccines, genetics, and cell therapy. Typical applications include :

1. Suspension cell and microcarrier cultures, microbial cultures

2. Process development

3.Process scale-up

4. Seed amplification of large-scale bioreactors

5. Production of clinical trial samples

6. Pilot-scale production

7. GMP scale production